Research and Information Network (B.R.A.I.N.)
Informational Resources on Brain Nutrition, Neuroethics, Brain Medicine, Neurobiological Pharmaceuticals, Neuroscience, Consciousness and Cognitive Enhancement
Introduction to the Brain
Brain Facts: A Primer on the Brain and Nervous System presented by the Society for Neuroscience pdf
Supplements: What Do You Know? What Should You Know?
The Council for Responsible Nutrition The Science Behind the Supplements
Neuroscience for Kids - Nutrition and the Brain an excellent introductory orientation on how diet and nutrition effects the brain.
E Reduces Mental Decline Among Older Persons
improve cognition in elderly women
nutrient supplements modify brain function?
antioxidant supplements and cognitive function in community-dwelling
Choline Supplements Make Brain Cells Larger, Faster
Alcohol and the Brain: Neuroscience and Neurobehavior a special report on the effects of alcohol on the brain
You (and Your Brain) are What You Eat by Andrew Weil, M.D
Rise in mental illness linked to unhealthy diets, say studies by Felicity Lawrence
Cognitive Health by Elizabeth Srejic
Effects of nutrition on brain development in humans by G Robert Delong, Division of Pediatric Neurology, Duke University Medical Center
The Healthy Brain Initiative: A National Public Health Road Map to Maintaining Cognitive Health presented by the CDC and Alzheimer's Association
Mental Health: A Report of the Surgeon General a superb report on the current state of brain and mental health
Mental health a concern for older people by Bill Mead
May is Mental Health Month, 'Mind Your Health' by Liz Atwell
Long-term Effects of Cognitive Training on Everyday Functional Outcomes in Older Adults The Journal of the American Medical Association (JAMA)
Milestones in Neuroscience Research by E.H. Chudler
Immune cells help maintain brain cell renewal by Judy Siegel-Itzkovich
Autistic brain never 'rests' by Megan Rauscher
Evolution of the Brain and Consciousness
of Consciousness Literature Review, Notes and Excerpts
Evolution of Primate Intelligence
Neuroethics and Cognitive Enhancement
The Oxford Centre for Neuroethics at Oxford University
Policy Implications of Technologies for Cognitive Enhancement The University of Arizona
Neuroethics Website at The University of Pennsylvania neuroethics.upenn.edu
Meeting Neuroethical Challenges in Cognitive Enhancement a recent conference on the ethical and social implications of cognitive enhancement.
Neuroethics: Mapping the Field Conference proceedings. Hosted by Stanford University and the University of California, San Francisco, May 13-14, 2002.
Battle for Your Brain Science is developing ways
to boost intelligence, expand memory, and more. But will you be allowed
to change your own mind?
Enhancers May 14, 1998
Is On for a Pill to Save the Memory New York Times,
July 29, 2003
Brain Gain: Drugs that Boost Intelligence by Julie Erlich
Cognitive Function Keeping your memory in tip top
Fear of a 'Cognitive Divide' Developing safe, specific,
powerful memory-improving drugs raises many ethical issues about the
implications of cognitive enhancement.
the Brain New drugs promise to improve memory and
sharpen mental response. Who should be allowed to take them?
Smart Drugs Federal and biotech labs research a new generation
of drug therapy that improves memory and concentration without side
pills' make headway
No 10 scientist urges brain pills for all by David Cracknell and Steven Swinford
Brain introductory article on brain structure, fields of study, and neurobiology
Neuroscience situates the discipline of neuroscience among related scientific research areas, delineates the history of the field, and lists major themes of research
Nootropics explores the different classes of nootropic substances (cholinergics, dopaminergics, and serotonergics) and their uses for depression, brain energy, concentration and memory enhancement
Groups and Usenet
BrainMeta sponsored by CerebralHealth.com
National Institutes of Health Seminar Series in Neuroscience online videos in neuroscience.
BrainMaps.org a high-resolution digital brain atlas based on scanned images of serial sections of monkey brains that is fully integrated with a high-speed database server for querying and retrieving data about primate brain structure and function over the internet.
Brain Conditions and Disorders Research
Can You Prevent Alzheimer's Disease? by Christine Gorman
Cognitive enhancement therapy for Alzheimer's disease. The way forward
Vitamin D: a natural inhibitor of multiple sclerosis
Department of Nutrition & Dietetics, Liberton Hospital, Lasswade Road, Edinburgh, UK
Cognitive Enhancement Therapy for Schizophrenia: Effects of a 2-Year Randomized Trial on Cognition and Behavior
Neurotransmitter Information and Research
Neurotransmitters and Neuroactive Peptides an introductory presentation on neurotransmitters
Brain Neurotransmitters by Ben Best
Acetlycholine a solid introduction to acetylcholine by Dr. William S. Messer, Jr., Professor of Medicinal and Biological Chemistry at The University of Toledo
Dopamine Wikipedia article
Serotonin and Its Uses by Andrea Byrd
Serotonin: The Neurotransmitter for the 90's by Ronald F. Borne, Ph.D., Department of Medicinal Chemistry, School of Pharmacy, University of Mississippi
Histamine by Dr. William S. Messer, Jr., Professor of Medicinal and Biological Chemistry at The University of Toledo
Norepinephrine in Psychiatry by John J. Spollen III, MD
Norepinephrine by Gary Aston-Jones
Epinephrine Wikipedia entry
Cognitive Enhancers Research Abstracts
1-year controlled trial of acetyl-l-carnitine in early-onset AD.
acetyl-L-carnitine and lipoic acid to old rats significantly improves
metabolic function while decreasing oxidative stress.
of the effects of acetyl l-carnitine and amantadine for the treatment
of fatigue in multiple sclerosis: results of a pilot, randomised,
double-blind, crossover trial
of acetyl-L-carnitine in Alzheimer's disease patients unresponsive
to acetylcholinesterase inhibitors
Cognition stimulating drugs modulate protein kinase C activity in cerebral cortex and hippocampus of …
Multicentre study of l-alpha-glyceryl-phosphorylcholine vs ST200 among patients with probable senile …
Effects of L-alpha-glycerylphosphorylcholine on the EEG power spectrum in the rat
Chronic L-alpha-glyceryl-phosphoryl-choline increases inositol phosphate formation in brain slices …
alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian …
Agents Enhance the Recruitment of Fast GABAA Inhibition in Rat Neocortex
Mechanism of Action of Aniracetam at Synaptic -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic
Acid (AMPA) Receptors: Indirect and Direct Effects on Desensitization
Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam
Physiology Graduate Program, University of California, San Francisco 94143-0450
AIT-082 Neotrofin, leteprinim potassium
a Cognitive Enhancer, Is Transported into Brain by a Nonsaturable
Influx Mechanism and out of Brain by a Saturable Efflux Mechanism
Scientific Basis for the Therapeutic Use of Withania Somnifera (Ashwagandha): A Review
Studies on the immunomodulatory effects of Ashwagandha
Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells
Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha
Modulatory effects of centrophenoxine on different regions of ageing rat brain
Age-related decline in multiple unit action potentials of CA3 region of rat hippocampus: correlation with lipid peroxidation and lipofuscin concentration and the effect of centrophenoxine.
Choline: A Vital Amine
Choline and Human Nutrition
Choline: an essential nutrient for humans
Choline: an important nutrient in brain development, liver function and carcinogenesis
Steven H. Zeisel, MD, PhD
Department of Nutrition, School of Public Health, School of Medicine, University of North Carolina at Chapel Hill, North Carolina
Docosahexaenoic Acid (DHA)
Benefits of Docosahexaenoic Acid (DHA)
acuity and the essentiality of docosahexaenoic acid and arachidonic
acid in the diet of term infants
in neuron size in docosahexaenoic acid-deficient brain.
effects of docosahexaenoic acid ethyl ester in patients with generalized
and Safety of Docosahexaenoic Acid and Arachidonic Acid Addition to
Infant Formulas: Can One Buy Better Vision and Intelligence?
by docosahexaenoic acid of age-induced alterations in gene expression
and molecular composition of rat brain phospholipids
enhancement, and the ethics of neurotherapeutics
Deacetylase Inhibitors as Cognitive Enhancers
An hypothesis on the role of glucose in the mechanism of action of cognitive enhancers
Cognitive enhancers in theory and practice: studies of the cholinergic hypothesis of cognitive …
Effects of four non-cholinergic cognitive enhancers in comparison with tacrine and galanthamine on …
… flow abolished by scopolamine is reversed by cognitive enhancers associated with cholinesterase …
Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to …
Cognitive enhancers and hippocampal long-term potentiation in vitro
AMPA receptor modulators as cognitive enhancers
… brain of the senescence-accelerated mouse: an animal model useful for studies on cognitive enhancers
CREB and the discovery of cognitive enhancers
Applications software as cognitive enhancers
for memory enhancement: a randomized controlled trial.
effects of Ginkgo biloba extract
Structure of acetylcholinesterase complexed with the nootropic alkaloid, (−)-huperzine A
Efficacy of tablet huperzine-A on memory, cognition, and behavior in Alzheimer's disease.
effects of an ergot alkaloid derivative (Hydergine) on aspects of
psychomotor performance, arousal, and cognitive processing ability
Sustained efficacy and safety of idebenone in the treatment of Alzheimer’s disease: update on a 2- …
A controlled study of 2 doses of idebenone in the treatment of Alzheimer’s disease
Idebenone in patients with Friedreich ataxia
Idebenone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in …
The effect of idebenone, a coenzyme Q analogue, on hydrophobic bile acid toxicity to isolated rat …
Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial
The response to levodopa in Parkinson's disease: imposing pharmacological law and order
A.M. Gotham, R.G. Brown and C.D. Marsden
From the MRC Movement Disorders Research Group, University Department of Neurology and Parkinson s Disease Society Research Centre, Institute of Psychiatry, London
Double-blind, placebo-controlled, fixed dose trial of minaprine in patients with major depression.
Minaprine, a new drug with antidepressant properties.
Oxiracetam prevents the hippocampal cholinergic hypofunction induced by the NMDA receptor blocker …
Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine
… of hippocampally-mediated learning and protein kinase C activity by oxiracetam in learning-impaired …
Clinical studies with oxiracetam in patients with dementia of Alzheimer type and multi-infarct …
Oxiracetam in dementia: a double-blind, placebo-controlled study
Oxiracetam prevents the MK-801 induced amnesia for the elevated plus-maze in mice
Oxiracetam in the treatment of primary degenerative and multi-infarct dementia: a double-blind, …
Oxiracetam increases the release of endogenous glutamate from depolarized rat hippocampal slices
Oxiracetam and aniracetam increase acetylcholine release from the rat hippocampus in vivo
Selegiline versus oxiracetam in patients with Alzheimer-type dementia
Comparative effects of amphetamine, phenylethylamine and related drugs on dopamine efflux, dopamine uptake and mazindol binding
EM Parker and LX Cubeddu
Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill
specific binding protein in rat brain: purification and characterization
improves activated blood flow and facilitates rehabilitation of poststroke
relieves symptoms in progressive myoclonus epilepsy: a multicentre,
randomised, double blind, crossover study comparing the efficacy and
safety of three dosages of oral piracetam with placebo
effect of the nootropic drug, piracetam on stress- and subsequent
morphine-induced prolactin secretion in male rats
and Study of Piracetam-like Nootropics, Controversial Members of the
Problematic Class of Cognition-Enhancing Drugs
Neurochemical studies on the mechanism of action of pyritinol.
On the effects of pyritinol on functional deficits of patients with organic mental disorders.
Activation PET as an instrument to determine therapeutic efficacy in Alzheimer's disease
Protection of cell proteins against free-radical attack by nootropic drugs: scavenger effect of pyritinol confirmed by electron spin resonance spectroscopy.
Neurochemical effects of pyritinol and their relevance for the treatment of brain function deficits in old age
Pyritinol hydrochloride and cognitive functions: influence on children in slow learner classes
Efficacy of pyritinol versus hydergine upon cognitive performance in patients with senile dementia of the Alzheimer's type: A double-blind multi-center trial
for cognitive impairment and dementia
Neuroscience Graduate School Rankings
1. University of California at San Diego San Diego, CA Stanford, CA San Francisco, CA Cambridge, MA Baltimore, MD New Haven, CT Columbia, NY St. Louis, MO Berkeley, CA Cambridge, MA 12. California Institute of Technology Pasadena, CA University of California at Los Angeles Los Angeles, CA 13. Philadelphia, PA Duke University Durham, NC 15. 16. Brandeis University Waltham, MA Seattle, WA Cleveland, OH 19. Ann Arbor, MI Austin, TX Chapel Hill, NC 22. Rockefeller University New York, NY University of Chicago Chicago, IL 23. 24. Emory University Atlanta, GA Boulder, CO
San Francisco, CA
New Haven, CT
St. Louis, MO
California Institute of Technology Pasadena, CA
University of California at Los Angeles Los Angeles, CA 13.
Duke University Durham, NC 15.
16. Brandeis University Waltham, MA
Ann Arbor, MI
Chapel Hill, NC
Rockefeller University New York, NY
University of Chicago Chicago, IL 23.
Emory University Atlanta, GA
Videos with Prof.
Douglas J. Phillips II, Director of R&D Part I: Introduction Part II: Frontal Lobes
Part I: Introduction
Part II: Frontal Lobes
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